slk or SLK may stand for:

SLK (album), a 2014 album by Stam1na SLK (gene), a gene that in humans encodes the enzyme STE20-like serine/threonine-protein kinase SLK (group), a British grime music group Adirondack Regional Airport, US (IATA code) Mercedes-Benz SLK-Class, a sports car Saaremaa Laevakompanii (Saaremaa Shipping Company), former Estonian ferry operator SilkAir (ICAO code) .slk, filename extension for the SYmbolic LinK (SYLK) format Slovak language (ISO 639-2 code) Starostové pro Liberecký kraj (Mayors for Liberec Region), Czech political party Super League Kerala, a men's professional franchise football league based in Kerala, India