System Shock is a 1994 first-person action role-playing video game developed by Looking Glass Technologies.

System Shock may also refer to:

System Shock (novel), 1995 novel written by Justin Richards System Shock (series), video game series System Shock (2023 video game), a remake of the 1994 video game System Shock (band), Swedish/Greek heavy metal band

See also Shock System, Malaysian rock band Shock to the System (disambiguation)