The Men's 400 metre freestyle S11 event at the 2016 Paralympic Games took place on 10 September 2016, at the Olympic Aquatics Stadium, in Rio de Janeiro, Brazil. No heats were held.

Final 19:52 10 September 2016:

Rank Lane Name Nationality Time Notes 4 4:28.78 3 4:40.96 6 4:41.05 4 5 4:43.17 5 2 4:48.71 6 7 5:02.38 7 1 5:06.77 8 8 5:30.66

Notes