Paoletti is an Italian surname. Notable people with the surname include:
Antonio Ermolao Paoletti (1834–1912), Italian painter Arturo Paoletti, Italian boxer Christian Paoletti (born 1984), Italian footballer Enzo Paoletti, Italian scientist Gabriele Paoletti (born 1978), Italian footballer Luigi Paoletti Vinea, 19th-century Italian painter Pietro Paolétti (1801–1847), Italian painter and engraver Roland Paoletti (1931–2013), British-Italian architect
See also Paleotti, another surname