Rue or Rué is a surname. Notable people with the surname include:

Gérard Rué (born 1965), French former cyclist Jean-Baptiste Rué (born 1974), French former rugby union player Joe Rue (1898-1984), American Major League Baseball umpire Joseph Rue, French World War II vice-admiral Lea Rue, stage name of Belgian singer-songwriter Emma Lauwers (born 1993) Loyal Rue (born 1944), American philosopher and writer Marcel Rué (born 1926), Monegasque sports shooter Nancy Rue, American Christian novelist Rob Rue, American politician Rosemary Rue (1928-2004), British physician and civil servant Sander Rue (born 1954), American politician Sara Rue, American television actress born Sara Schlackman in 1979