Mayor of Harlem is an honorific title that may refer to:
Willie Bryant (1908–1964), bandleader Tommy Smalls (1926–1972), disc jockey Leslie Wyche (1944–2018), community activist Greg Bandy (1949–), drummer Alpo Martinez (1966–2021), drug dealer Queen Mother Dr. Delois Blakely, nun and activist See also De Mayor of Harlem, a 1985 book of poetry by American David Henderson