Wyeth is an unincorporated community in Andrew County, Missouri, United States.

Description The community is on Route C approximately southeast of Rosendale. The One Hundred and Two River flows past about to the west.Missouri Atlas & Gazetteer, DeLorme, 1st ed, 1998, p. 19

History An old variant name was Rush, after Peter Rush, a local landowner. A post office called Rush was established in 1890, the name was changed into Wyeth in 1904, and the post office closed in 1905.

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