The light novel Re:Zero and its derivative anime and manga adaptations feature a cast of characters created by Tappei Nagatsuki and designed by Shinichirou Otsuka.

Main characters

Voiced by (English): Sean ChiplockVoiced by (Japanese): Yūsuke Kobayashi The main protagonist of the series, Subaru is a 17-year-old NEET who suddenly finds himself teleported to another world on his way home from the convenience store. There, he meets a silver-haired half-elf girl named Emilia, and falls deeply in love with her. Upon his arrival, Subaru acquires an ability which he calls , that allows him to go back in time when he dies, while still retaining his memories of the previous timeline.

Voiced by (English): Kayli MillsVoiced by (Japanese): Rie Takahashi The main heroine, Emilia is a silver-haired half-elf girl and a Spirit Art User; she is one of the candidates to become the next ruler in the royal election, which would make her the 42nd Queen of Lugunica. Subaru first meets her when her insignia, which she needs to possess in order to be eligible to participate in the election, is stolen by Felt. She is from the Frozen Forest, and is over a hundred years old (although most of the time she was frozen in the forest). Her mental state is still that of a teenager. The name Emilia first used when introducing herself to Subaru, "Satella", is also the name of the "Witch of Envy", whose appearance is said to resemble her own and is responsible for the discrimination against half-elves. Among the half breeds and other discriminated or disenfranchised races and people in Lugunica, she is seen as their hope for a better future due to her ideal of democracy and better social equality. Because of her heritage and resemblance to Satella, however, Emilia is often shunned and hated by most people, leaving her lonely and without any friends prior to meeting Subaru. Initially, she regards Subaru as a mischievous child who always needs to be taken care of. After he risks his life to save her from the Witch's Cult, however, Emilia starts to develop deep feelings for him, as Subaru is the first person to ever make her feel truly happy, accepted and loved.

Supporting characters Emilia's Faction

Voiced by (English): Erica MendezVoiced by (Japanese): Yumi Uchiyama Emilia's familiar and a spirit in the form of a cat. His work time is from 9a.m. to 5p.m., similar to a salaryman's. He has an empathic ability that allows him to read people's minds through their emotions/intent. Should Emilia ever die, Puck turns into a huge beast intent on destroying the world, since Emilia, the purpose of his existence, is gone. His true identity is that of "Beast of the End of the Eternally Frozen Lands", one of 4 Great Spirits of the world who can control heat. The character won the award for Best Character (Mascot) in the 2015–2016 Newtype Anime Awards.

Voiced by (English): Ray ChaseVoiced by (Japanese): Takehito Koyasu A Margrave, as well as an Imperial Wizard and Count who is a benefactor and sponsor for Emilia's bid for the throne. He has an appearance and affect that lead to Subaru initially mistaking him for a clown. He is a highly influential individual who is also one of Lugunica's most powerful mages. It is revealed that his reason for supporting Emilia is for him to kill the Dragon. It is eventually revealed that he is actually far older than he appears, having possessed the bodies of his descendants in hopes of living long enough to revive Echidna, his master and the love of his life.

Voiced by (English): Brianna KnickerbockerVoiced by (Japanese): Inori Minase One of the twin demons who work at Roswaal's mansion as maids, Rem is Ram's twin sister. She has blue hair which she wears parted on the left, and still has a full horn, which grants her magical power. She does work at the mansion, although her ability to cook is better than her sister. She used to have an inferiority complex towards her sister. Bearing an intense hatred for the Witch's Cult, Rem initially hates Subaru for having the scent of the Witch on him and kills him. After Subaru saves her from the mabeasts of Elior Forest, however, Rem discards her suspicions and falls deeply in love with him, and even when he turns her down in favor of Emilia, she still becomes one of his most loyal followers. An extra story in Arc 3 of the novel tells a "What If" story about what could've happened if Subaru and Rem had decided to run away instead; they lived happily ever after with two children. The character has become popular with fans of the series, leading to a hug pillow featuring the character being delayed due to unanticipated demand. She was also the eighth ranked female character in the August issue of Newtype's monthly character polls, and fifth ranked in the September issue, before rising to first place in the October issue. Her rank began to decline after that, slipping to third and then seventh place in the November and December issues. She won the award for Best Character (Female) in the 2015–2016 Newtype Anime Awards, as well as first place on a list of "most popular two-dimensional character" based on a poll of Otamart users. The character won the Best Girl award at The Anime Awards 2016.

Voiced by (English): Ryan BartleyVoiced by (Japanese): Rie Murakawa One of the demons who work at Roswaal's mansion as maids, Ram is Rem's twin sister. She has pink hair which she wears parted on the right. Together, the twins often make sarcastic remarks towards Subaru. Ram always calls Subaru "Barusu", and rarely shows any respect for him. Despite twins being prohibited in their clan, the two were spared due to Ram being a prodigy at a young age. She lost her powers after her horn was cut off during the attack on their village by the Witch's Cult. Outside of magic, Ram only excels Rem in cleaning, whereas Rem is far superior to Ram in almost all other tasks, contrary to Rem's constant praise of Ram. Ever since losing her horn, her body has become very weak with low stamina and magic powers. It is shown that master Roswaal helps heal her daily.

Voiced by (English): Kira BucklandVoiced by (Japanese): Satomi Arai A mysterious girl who was contracted by Roswaal to keep his ancient magical tomes safe in his enormous library. She has the ability to warp any room in the mansion to this library whenever she chooses, but cannot completely leave the mansion. She tends to suffix many of her sentences with "I suppose", and has a deep affection for Puck. Despite her cold behavior and verbal abuse towards Subaru, stemming from his ability to easily guess where she is located and tendency to barge into the library without asking, Beatrice cannot stand if people are hurt in front of her and becomes one of the people that Subaru can trust. During Arc 4 of the web novel, she is revealed to be an artificial spirit and forms a contract with Subaru at the end. She is about four hundred years old.

Voiced by (English): Zeno RobinsonVoiced by (Japanese): Nobuhiko Okamoto Garfiel Tinzel is a demi-human who guards the Sanctuary and is Frederica Baumann's half-brother with both of them having the same mother. He serves as a secondary antagonist in the first half of Arc 4, but later joins the Emilia Camp after his defeat at the hands of Subaru and getting over his past.

Voiced by (English): Dawn M. Bennett; Faye Mata (episode 11)Voiced by (Japanese): Kaori Nazuka A demi-human maid who works in another mansion that belongs to relatives of Roswaal, House Miload. She made a cameo appearance in episode 11. She returns to the Roswaal mansion at the beginning of Arc 4 to fill in for the erased Rem. She left the Sanctuary ten years prior to the events of Arc 4, in order to find a safe haven for the citizens of the Sanctuary if and when the barrier surrounding the Sanctuary is lifted.

Voiced by (English): Erik Scott KimererVoiced by (Japanese): Kouichi Souma Subaru's female black Land/Ground Dragon which he received as a gift from Crusch. It's of the Diana breed which are known for their fierce temperament and strong pride. Surprisingly enough though, she has taken quite a liking to Subaru, sometimes in a maternal like way.

Voiced by (English): Zach AguilarVoiced by (Japanese): Kōhei Amasaki A traveling merchant Subaru meets in Arc 3 en route to Roswaal's territory, who was drunk and down on his luck. While he can be somewhat skittish and cowardly he's generally a well meaning person and very loyal to those who earned his friendship. In the light novel, he states out of all the candidates Otto supports Emilia the most because, like her, he is used to being misunderstood and treated badly for being different. He has a blessing that allows him to communicate with any animal, plant or being in the world. Unfortunately, this tends to unsettle people and makes him come across as shady and sinister when it is in use. He joins Emilia's camp in Arc 4 and helps to defeat Garfiel.

Voiced by (English): Erica MendezVoiced by (Japanese): Marika Kōno One of the village children whom Subaru befriends, who planned to become a seamstress in the capital one day. She develops a crush on him after he saves her and the village twice, and later works as a maid in Roswaal's mansion to fill in for Rem in the 4th Arc becoming an official member.

Ruler Candidates

Voiced by (English): Christine Marie CabanosVoiced by (Japanese): Chinatsu Akasaki A 15-year-old thief who grew up in the slums of the capital. She initially appeared as a thief who stole Emilia's insignia and attempted to sell it to the highest bidder. Subsequently, Emilia's insignia reacted to her, making Felt a worthy candidate for the next ruler in royal election. Due to her difficult upbringing, Felt supports anarchism in order to destroy the current system. It is later revealed that she might be related to the royal family due to her appearance resembling them, but there is no way to confirm this because all of them are currently deceased. It is later revealed in arc 5 that Felt is not her real name.

Voiced by (English): Faye MataVoiced by (Japanese): Yukari Tamura One of the candidates for the royal election to become the 42nd Queen of Lugunica and head of House Barielle. Men are captivated by her beauty. Priscilla has an extravagant self-centered personality and supports totalitarianism where everyone must treat her with divinity, because of how much the world turns into her favor. Even though she is only 19, Priscilla had 8 husbands who have all "mysteriously" died; despite that, lands she has acquired have prospered under her thanks to her almost supernatural good luck.

Voiced by (English): Cassandra Lee MorrisVoiced by (Japanese): Kana Ueda One of the candidates for the royal election to become the 42nd Queen of Lugunica, who speaks in "Kansai" dialect. She is the 22-year-old head of the famous Hoshin Trading Company and has been billed as second coming of the company's founder "Hoshin of the Wilderness" for her near unprecedented success in business, which she hopes to use for Lugunica via capitalism. Anastasia likes it when people benefit while she benefits, despite her greed as an orphan, and is actually sympathetic. She hails from Kararagi, which lies west of Lugunica and has a personal mercenary company known as the "Iron Fang".

Voiced by (English): Erika HarlacherVoiced by (Japanese): Yuka Iguchi