Calcagno is an Italian surname. Notable people with the surname include:
Domenico Calcagno (born 1943), Italian cardinal Eric Calcagno (born 1967), Argentine sociologist, journalist, diplomat and politician Fortunato Calcagno (1900–1966), Italian lawyer, politician and officer Francesco Calcagno (1528–1550), Franciscan friar Giuseppa Bolognara Calcagno (1826–1884), Italian revolutionary Lawrence Calcagno (1913–1993), American painter Raimundo Calcagno (1906–1982), Argentine film critic, journalist and screenwriter Robert Calcagno (born 1960), Monegasque politician Umberto Calcagno (born 1970), Italian footballer
See also Calcagno (cheese)