Cenci () is an Italian surname derived from the medieval given name Cencio. Notable people with the name include:

, a noble family of Renaissance Rome, including: Beatrice Cenci (1577–1599), Italian noblewoman and parricide (1676–1740), Italian cardinal Athina Cenci (born 1946), Greek-Italian actress and comedian Antinisca Cenci (born 1978), Italian equestrian Baldassare Cenci (seniore) (1648–1709), Italian Roman Catholic cardinal Baldassare Cenci (iuniore) (1710–1763), Italian Roman Catholic cardinal Cecilia Cenci (1942–2014), Argentinian actress Christian Cenci (born 1998), Italian football player Gaspare Cenci (), Italian Roman Catholic prelate Giuliano Cenci (1931–2018), Italian animated film director John Cenci (born 1934), American football player Massimo Cenci (born 1967), Sammarinese politician Matías Cenci (born 1978), Argentine football player Mirco Cenci (born 1957), Italian sports shooter

See also The Cenci, a drama by Percy Shelley based on Beatrice's murder of her father The Cenci (opera), an opera adaptation by Havergal Brian Les Cenci, a drama adaptation by Antonin Artaud Beatrice Cenci (disambiguation) Beatrix Cenci, Alberto Ginastera's opera Lungotevere De' Cenci, Rome Cenci Journalism Project (), which aims to use multilingual and global sources in Chinese journalism Censi (surname)

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