Brignoli is an Italian surname. Notable people with the surname include:
Alberto Brignoli (born 1991), Italian footballer Ermanno Brignoli (born 1969), Italian cyclist Luca Brignoli (born 1983), Italian footballer Mario Brignoli (1902–1990), Italian racewalker Paolo Brignoli (1942–1986), Italian entomologist Pasquale Brignoli (1824–1884), Italian-born American opera singer Tommaso Brignoli (born 1999), Italian footballer
See also
Brignolia, a genus of goblin spiders Lawrence Brignolia (1876–1958), American long-distance runner and rower