Kupferman is a surname. Notable people with the surname include:

Fred Kupferman (1934–1988), French historian Laurent Kupferman (1966–2025), French essayist and author Lawrence Kupferman (1909–1982), American artist Meyer Kupferman (1926–2003), American composer and clarinetist Moshe Kupferman (1926–2003), Israeli artist Orna Kupferman, Israeli computer scientist Theodore R. Kupferman (1920–2003), American politician