Gioffre is a given name and surname. Notable people with the name include:
Anthony B. Gioffre (1907–1996), American lawyer and politician Gioffre Borgia ( 1481– 1516), Italian noble, illegitimate son of Pope Alexander VI and brother of Lucrezia and Cesare Borgia Gioffré (drag queen), Italian drag queen
See also Jofre (name)