Gandolfo is a surname. Notable people with the surname include:
Antonino Gandolfo (1841–1910), Italian painter Carlos Gandolfo (1931–2005), Argentine actor and theatre director Emanuel Gandolfo (born 1968), Argentine stage magician Giancarlo Gandolfo (born 1937), Italian economist Jarett Gandolfo, American politician Mike Gandolfo (born 1958), American tennis player
See also Castel Gandolfo, a town in the Italian region of Lazio Gundulf