Pedrazzini is an Italian surname. Notable people with the surname include:
Members of the Pedrazzini family from Campo (Vellemaggia), a wealthy family of Swiss merchants attested since the 17th century Giovanni Battista Pedrazzini (1673–1749) Maria Apollonia Pedrazzini (1693–1766) Michele Pedrazzini (1712–1763) Guglielmo Maria Pedrazzini (1733–1801) Giuseppe Pedrazzini (1879–1957), Italian luthier Luigi Pedrazzini (footballer) (1909–?), Italian footballer Massimo Pedrazzini (born 1958), Italian footballer and manager Mauro Pedrazzini (born 1965), Liechtenstein politician