Mamatov (masculine, ) or Mamatova (feminine, ) is a Russian and Turkic surname. Notable people with the surname include:
Bakytbek Mamatov (born 1980), Kyrgyzstani footballer Jahangir Mamatov (born 1955), Uzbekistani writer and politician Natalya Mamatova (born 1985), Uzbekistani taekwondo practitioner Viktor Mamatov (1937–2023), Soviet biathlete