Swerdlow is a surname. It is an altered form of the surname Sverdlov. Notable people with the surname include:
Amy Swerdlow, American activist Anthony Swerdlow, British epidemiologist Ezra Swerdlow (1953–2018), American film producer Jenna Rose Swerdlow (born 1998), American singer Joel Swerdlow, American journalist Mark Swerdlow (1918–2003), British consultant anaesthetist Michael Swerdlow (born 1943), American real estate developer Noel Swerdlow (1941–2021), American academic Tommy Swerdlow (born 1962), American screenwriter
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