Bortoletto is a surname of Italian origin. Notable people with the surname include:
Albano Bortoletto Cavallin (1930–2017), Brazilian Roman Catholic prelate Daniela Bortoletto, Italian-British high energy physicist Gianni Bortoletto (born 1956), Italian football manager Raoul Bortoletto (1925–2003), Italian professional footballer
See also Gabriel Bortoleto, Brazilian racing driver