Pseudotropine (3β-tropanol, ψ-tropine, 3-pseudotropanol, or PTO) is a derivative of tropane and an isomer of tropine. Pseudotropine can be found in the Coca plant along with several other alkaloids Synthesis In the laboratory it is made by the reduction of tropinone: According to the article, good stereoselectivity of pseudotropine over endotropine could be achieved when employing a Meerwein–Ponndorf–Verley reduction or sodium metal in n-pentanol.
Derivatives Pudafensine Tropigline (Tigloidine, ticloidine) [533-08-4] (E)-form Produced by Physalis peruviana. Anticholinergic, anti parkinsonian drug.Beresford, P. J., Woolley, J. G. (October 1974). "Biosynthesis of ticloidine in Physalis peruviana". Phytochemistry. 13 (10): 2143–2144. doi:10.1016/0031-9422(74)85016-8.Barger, G., Martin, Wm. F., Mitchell, Wm. (1937). "383. The minor alkaloids of Duboisia myoporoides". Journal of the Chemical Society (Resumed): 1820. doi:10.1039/jr9370001820.Rabot, S. (May 1995). "Tigloyl-CoA:pseudotropine acyl transferase—An enzyme of tropane alkaloid biosynthesis". Phytochemistry. 39 (2): 315–322. doi:10.1016/0031-9422(94)00907-B. Convolamine Valtropine Pseudotropine benzoate (tropacocaine)
See also Pseudotropine acyltransferase Atropine Tropine Tropinone
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