Wolfrum is a surname. Notable people with the surname include:
Chet Wolfrum (1910–1973) American politician Rüdiger Wolfrum (born 1941), German professor of international law at the Heidelberg University Faculty of Law and director emeritus Walter Wolfrum (1923–2010), German World War II fighter ace William Wolfrum (1926–2007), suffragan bishop of the Episcopal Diocese of Colorado from 1981 to 1988