Bartolomé de Ledesma, O.P. (died February 16, 1604) was a Roman Catholic prelate who served as Bishop of Antequera, Oaxaca (1583–1604) (in Latin) and Bishop of Panamá (1580–1583).Arzobispo de Panama Guillermo Rojas y Arrieta C.M. Resena Historica de los Obispos que han ocupado la silla de Panama Publisher: Escuela Tipográfica Salesiana (1929) | pp. 26–28Los Obispos Latinoamericanos - Defensa Del Indio pp. 30–31 | retrieved November 17, 2015

Biography Bartolomé de Ledesma was born on February 16, 1604, in Salamanca, Spain and ordained a priest in the Order of Preachers. On October 20, 1580, Pope Gregory XIII appointed him Bishop of Panamá (some sources state that he did not accept the nomination). On June 3, 1583, he was consecrated bishop by Diego de Romano y Govea, Bishop of Tlaxcala (Puebla de los Angeles). As there was no official governor during his term as bishop of Panama, he was instrumental in governing the province with the Audencia Real (high court). He reached out to the Cimarrónes (free blacks) who were living outside of the Crown's jurisdiction and facilitated their incorporation into the colony. In 1581, a treaty was signed between the Cimarrónes which gave them the land which they possessed and allowed them to found and settle the city of Pacora, near Panama City, as a commercial center. He also helped to lessen congestion in Panama City by founding the town of Penonomé and establishing parishes in Natá and Olá. In June 1584, Pope Gregory XIII appointed him the third Bishop of Antequera, Oaxaca. In 1585, he attended the Third Mexican Provincial Council.

Ledesma died on February 16, 1604.

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