Mayo is a given name. Notable people with the name include:
, Japanese women's footballer Mayo Kawasaki (born 1963), Japanese actor Mayo Hibi (born 1996), Japanese tennis player , Japanese synchronized swimmer Mayo Methot (1904–1951), American actress, third wife of Humphrey Bogart Mayo Okamoto (born 1974), Japanese singer-songwriter Mayo Smith (1915–1977), American baseball player and manager Mayo Suzukaze (born 1960), Japanese actress Mayo Thompson (born 1944), American musician and visual artist Mayo Yamaura (born 1984), Japanese curler J. Mayo Greenberg (1922-2001), American astrophysicist