Ahuizotl may refer to:

Ahuitzotl, also transcribed Ahuizotl, an Aztec emperor (r. 1486–1502) Ahuizotl (mythology), a Mesoamerican mythological creature Ahuizotl (Dungeons & Dragons), a creature from Dungeons & Dragons Ahuizotl, a My Little Pony: Friendship Is Magic character