9 Chickweed Lane is an American comic strip written and drawn by Brooke McEldowney for over 30 years, which follows the fortunes of the women of three generations of the Burber family: Edna, Juliette, and Edda. 9 Chickweed Lane is the address of the characters' former family home. There is occasional overlap of characters between 9 Chickweed Lane and another comic by McEldowney, Pibgorn.

The strip is syndicated by United Feature Syndicate (a division of Andrews McMeel Syndication). It debuted on July 12, 1993. It won the National Cartoonists Society Award for Newspaper Strip in 2005, and has been given Genesis Award Commendations for bringing attention to animal rights.

Publication Syndicated by United Media, 9 Chickweed Lane debuted on Monday, July 12, 1993, though comics historian Don Markstein notes that some sources erroneously give August 2, 1993.

McEldowney's comic strip primarily focuses on the relationships between its multigenerational female characters, beginning with a single mother, Juliette, and her teen-aged daughter, Edda. Although he did not originally intend to have the characters age, they have done so, though not at real-time.

The comic has dealt with a number of difficult issues including pregnancy out of wedlock, a school shooting, and the impact of sexuality on religious vocations. It has been criticized for addressing such topics, to the point of being removed from some newspapers. It has been both acclaimed and criticized for its "libidinous hot-plot lines" and the enthusiastic sexuality of its characters. In a column entitled The Unbearable Horniness of 9 Chickweed Lane, critic Nathan Rabin criticized the strip's recurring sexual themes, writing "It feels like the only 'gag' in 9 Chickweed Lane is how unbelievably horny all the characters are for each other." Rabin is also critical of the strip's "intellectual pretensions" and McEldowney's "unspeakably pretentious, self-satisfied, endlessly masturbatory" content.The Unbearable Horniness of 9 Chickweed Lane, Nathan Rabin's Happy Place, May 6, 2020

Design 9 Chickweed Lane was originally drawn by hand in black and white. Around 1995, McEldowney moved to digitally-based production, using his computer as a drawing tool. The comic eventually introduced color at the publisher's insistence.

McEldowney trained as a musician and incorporates dance and music into his drawings: several of his characters are dancers, singers, or musicians. One reviewer writes "Dance strips or strips involving just hands, hands hold hands, arms moving, legs moving, are gorgeous and dynamic." Another comments on the Zen-like slowness of McEldowney's sequences, describing his work as lingering on the page, as he often draws out the action across multiple days. Even reviewers who dislike the comic for other reasons have applauded its design qualities:

Characters Edda van Hoesen (née Burber) – Independent and intelligent with a heroic fantasy life as Superlative Girl, she is a talented, attractive ballet dancer and a skilled piano recitalist who has done modeling for the fictional ladies apparel line Nicolette Cignet. She also holds a black belt in an unspecified martial art. Edda graduated early from her Catholic high school and moved to New York City. Although she had frequently displayed sexual attraction to her ballet partner Seth, she married her longtime sweetheart Amos on September 11, 2017. On December 12, 2019, she found out she was pregnant with twin girls, who were born in the first week of March 2020. Juliette Martine Kiesl (née O'Malley, formerly Burber) – Divorced (from Jack) and the single mother of Edda, she is the daughter of Edna O'Malley. Juliette has a creative fantasy life (her alter-ego is the leopard skin-clad Panther Woman) but is competent at achieving her goals in reality. A Fulbright scholar, after being a biology professor at a New Hampshire university, she followed her dream of owning and operating a farm. She later married Elliott Greene in a ceremony officiated by Thorax, and eventually returned to the school in a part-time position. She learned she is the product of a brief relationship her mother had with an Austrian opera singer, Peter Kiesl, and later took on his family name. She was named after her stepfather's first wife, Martine Juliette. Edna "Edie" Ernst O'Malley/Eva Kiesl – Mother of Juliette and grandmother of Edda. "Gran" is irascible and argumentative, though loving. In her youth she was a beautiful, talented USO singer and spy for Allied Intelligence during World War II. Much of her life is told in an extended year-long flashback sequence, begun in October 2009, that has been described as "ambitious, moving, and still often pungently funny" and "one of the most engrossing and well-told stories from this year". During that time she had a relationship with Lt. Peter Kiesl, an Austrian Wehrmacht POW in England, which they rekindled ten years later in New York City when he was a visiting singer for the Metropolitan Opera; this led to a very brief engagement and the conception of Juliette. Afterward, Edna married Bill O'Malley, with whom she had a second child (Roger), and was later widowed. After Kiesl, who she thought had recently died, visited her in New Hampshire to express his continued love for her, Edna moved to Vienna and married him. Amos van Hoesen – A geeky, talented classical cellist and Edda's husband, who occasionally accompanies her in performance. Best friends since childhood that blossomed into love, he graduated from the same school as she and went on to study at Juilliard. They finally consummated their love after Edda performed a dance with Amos providing a piano accompaniment in November 2004, renewed their love at a music competition in Belgium and wedded after a lengthy courtship and engagement. They have since become parents to twin daughters Polly and Lolly. Thorax – Formerly Gran's gentleman friend, he is brilliant and odd beyond all description. Apparently a large, amiable elderly farmer, he does not appear to be quite human, and has a quantum anomaly in his tractor shed. Thorax and Edna dated a few years until Edna's reunion with Kiesl. He also appears in McEldowney's online strip Pibgorn. On Oct. 4, 2017 he was revealed to be Sven's father. He claims to be married to Esme Meadow, and have the name William Meadow. In a storyline commencing September 2021 Thorax recalls joining the Canadian RAF during WW2 and becoming romantically involved with Polish double-agent Zofia Przyjukylska. Pap – Thorax's father is aged beyond reckoning, with a classic Yankee-farmer acerbic mien. Elliott Greene – Juliette's love interest, and her co-worker at the university. In January 2006, Juliette accepted the most recent in his long series of marriage proposals, and they were married by Thorax. Seth Appleby – Edda's dancing partner and housemate, a physically imposing, handsome bisexual with a boyfriend and an occasional indulgence with a female partner. In a storyline that began at the start of Pride Month 2021, he began cheating on his boyfriend with Fernanda Jons, eventually culminating in their marriage. Mark – Seth's live-in boyfriend until July 2021; an artist and gallery owner. Fernanda Jons – Seth's former female friend-with-benefits, a ballerina from Argentina who was temporarily partnered with him in the ballet company. Dream sequences throughout July 2021 have her as a recurring fantasy of Seth's, and he asks her to marry him in the July 17th strip. In the July 28th strip, it is revealed that Fernanda has had knee surgery and can no longer dance. She and Seth married on September 1, 2021. Janice – A friend of Edda's from the ballet company. She has a crush on Mark, who remains her friend while gently rebuffing her advances. Isabel Florin – A pianist with a narcissistic bent who accompanies Amos' practice on cello, she likes Amos and has been in conflict with Edda over this. She is of Portuguese origin with a slight accent. Burkhardt Kriegl – A violist from Vienna. A womanizer regularly rebuffed by Edda, he took up with Isabel. Fleurette ("Fleurrie") Spocket – The veterinarian who came to treat Juliette's sick bull and was once a student in her biology class. She married her longtime veterinary technician, Sven. Sven Spocket – Fleurrie's tall, sweet and handsomely hulking, if slightly naive, veterinary technician, formerly a gutter cleaner. They eventually married. He is fluent in four languages and has a Ph.D. in art history (French Rococo, specializing in Jean-Honoré Fragonard). On October 4, 2017, he was revealed to be Thorax's son. Sister Steven – a Mother Superior who runs the Catholic school Edda and Amos once attended. An archetypically strict nun with no sense of humor and nicknamed as "Sister Caligula" by her students, she does occasionally show a human side to her nature. Her birth name was Florence Anne Feeney, and her brother is Cardinal Feeney. Diane Durly – Formerly Sister Aramus, a nun who used to teach English at the Catholic high school that Edda and Amos attended. She left her vocation after falling in love with Francis Durly. They married in the October 30, 2007 strip, after a long courtship and became parents to a daughter, Florence Anne, in the October 6, 2011 strip (after Sister Steven's name before she became a nun) and has since become a mother to five more children, according to the March 10, 2020 strip. Two years later, she had given birth to three more children. Francis Durly – A former Catholic priest who left his vocation after falling in love with Diane, whom he married. Mary Rosenzweig – Edda and Amos' classmate from their Catholic high school. Amos used to pursue her for affection, but was always rejected. In more recent times, she's been married and divorced twice; the first husband having two affairs on the side and in the second marriage, she had her own infidelity. Solange – Edda's Siamese cat, who appears in ongoing thread of strips focused on her, Hallmarks of Felinity.The collection is also available as a book, Hallmarks of Felinity, The cat who would become Solange first appeared on March 23, 1999. Originally, the animal characters in the strip consisted of a whippet named Rudyard, succeeding a greyhound named Divot, and a spot-eyed cat, Ambrose. Rudyard and Ambrose often held mental conversations regarding their human owners, when Rudyard wasn't chucking insults at the cat's naïveté. Solange soon replaced Ambrose after her introduction, and the greyhound disappeared from the strip as well. Monty – God in the form of a bald man wearing a suit or else a delusional man who has convinced Thorax that he is indeed God; a test of Monty's powers made him appear to be embarrassed at his inability to pull off even a minor task. Earl William "Bill" O'Malley – Gran's late husband and Juliette's stepfather. As a young lieutenant during World War II, he saw Edna perform for the Allied troops and helped recruit her for a spying mission at a British POW camp housing German prisoners. Seriously injured on D Day, he suffered severe amnesia, met and fell in love with his French Resistance contact Martine Clocqueur, and was briefly married to her. Years later he married Edna and moved to Omaha, Nebraska, to have a long, unfulfilled marriage. Bill is the father of Edna's second child, Roger, who is rarely mentioned and was not seen in the strip until November 22, 2010. Martine Juliette Clocqueur-O’Malley – A beautiful, feisty French Resistance operative who worked as a double agent with the Nazi German forces during the occupation of France during World War II and was Bill's contact during D-Day. She and Bill fell in love and were married within days of the Liberation of Paris. She was mortally wounded very shortly afterward.