Bertino is an Italian surname. Notable people with the surname include:
Al Bertino (1912–1996), American animator Bryan Bertino (born 1977), American film director, producer and screenwriter Claus Bertino (born 1980), Danish boxer Elisa Bertino, Italian computer scientist Joseph R. Bertino (1930–2021), American researcher in the cancer pharmacology program Marie-Helene Bertino, American novelist and short story writer Tom Bertino, American animator Anthony W. "Chip" Bertino, Jr., American Publisher and elected official
See also Jennifer Bertino-Tarrant Niia (born Niia Bertino), American singer, pianist, and songwriter