James Wise may refer to:
James Wise (civil surgeon) (died 1886), British civil surgeon in Dhaka, British India James E. Wise Jr., U.S. Navy officer James H. Wise (bishop) (died 1939), bishop of Kansas in the Episcopal Church James H. Wise (politician) (1912–1976), American politician James W. Wise (1868–1925), U.S. Representative from Georgia James Wise (born 1986), British venture capitalist
See also Jim Wise (born 1964), American actor Jim Wise (composer) (1919–2000), American musical composer and English professor Thomas James Wise (1859–1937), British bibliophile