Rubus nefrens is a rare North American species of brambles in the rose family. It has been found in scattered locations in the central United States, in Missouri, Iowa, Kentucky, and Ohio. Nowhere is it very common.Biota of North America Program 2014 county distribution mapBailey, Liberty Hyde 1925. Gentes Herbarum; Occasional Papers on the Kinds of Plants 1(5): 239, figure 111

The genetics of Rubus is extremely complex, so that it is difficult to decide on which groups should be recognized as species. There are many rare species with limited ranges such as this. Further study is suggested to clarify the taxonomy.Flora of North America, Rubus Linnaeus, 1754. Bramble

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External links Photo of herbarium specimen at Missouri Botanical Garden