Opie is a surname, a given name and a nickname. Notable people with the name include:
Given name or nickname Opie Cates (1909–1987), American clarinet player Gregg Hughes, American radio personality, known by his air name Opie, former co-host of Opie and Anthony Opie Ortiz, American artist specializing in tattoos, pop art and murals Otto P. Weyland (1903–1979), United States Air Force general
Surname Alan Opie (born 1945), British baritone singer Amelia Opie (1769–1853), English author; the wife of John Opie Catherine Opie (born 1961), American artist and photographer Chris Opie (born 1987), British racing cyclist Eugene Lindsay Opie (1873–1971), American pathologist Iona Opie (1923–2017), British specialist in children's literature and the customs of schoolchildren; the wife of Peter Opie John Opie (1761–1807), Cornish historical and portrait painter; the husband of Amelia Opie John N. Opie (1844–1906), American politician Julian Opie (born 1958), British artist known for his use of vector-based reproductions June Opie (1924–1999), New Zealand polio survivor and writer Lisa Opie (born 1963), English squash player Peter Opie (1918–1982), British specialist in children's literature and the customs of schoolchildren; the husband of Iona Opie Redvers Opie (1900–1984), British economist Robert Opie (born 1947), British item collector and the director of the Museum of Brands, Packaging and Advertising; son of Iona and Peter Opie Roger Opie (1927-1998), Australian-born Economist, Rhodes Scholar and Oxford academic
Fictional characters Opie (Family Guy), on the animated TV series Family Guy Opie, a squirrel on the animated TV series Capitol Critters Opie, the titular character of the American film Opie Gets Laid Opie, Happy Lowman's beloved dog (named after the Sons of Anarchy SAMCRO member Opie Winston) that plays a pivotal role in Mayans M.C. season 2 Opie Taylor, on the TV series The Andy Griffith Show Opie Winston, a SAMCRO member on the TV series Sons of Anarchy