Yazzie is a name, derived from the Navajo word meaning "little" and may refer to:
Yazzie Johnson (born 1946), Navajo jeweler living in northern New Mexico Aaron Yazzie (born 1986), Navajo mechanical engineer working at NASA's Jet Propulsion Laboratory Allan Yazzie, Navajo educational advocate Aneva J. Yazzie, American and Navajo industrial engineer Brian Yazzie, known as Yazzie the Chef, Navajo chef Cherilyn Yazzie, American and Navajo politician, farmer, and entrepreneur Jolene Yazzie (born 1978), Navajo graphic designer in Arizona Melanie Yazzie (born 1966), Navajo printmaker, sculptor, and professor in Colorado Rhiana Yazzie, Navajo playwright, actor, and filmmaker Sybil Yazzie (1916–2002), Navajo painter Steven Yazzie (born 1970), Native American artist