Michael Shapiro may refer to:

Michael Shapiro (actor) (born 1965), American actor, voice actor and theatre director Mike Shapiro (programmer), American computer programmer Michael J. Shapiro (born 1940), American political scientist at the University of Hawai'i Michael Jeffrey Shapiro, American composer and music director of the Chappaqua Orchestra Michael Shapiro (journalist) (1910–1986), British journalist and translator Mike Shapiro, bookmaker, see Sands Hotel and Casino

See also Mikhail Chapiro (born 1938), Russian artist and painter, currently lives in Canada