Karen A. Duncan is a biostatistician and health informatics specialist, who was named a Fellow of the Association for Computing Machinery in 2000.ACM Fellow award citation, retrieved 2015-06-30: "Karen has been an outstanding researcher, writer, innovator, and leader in medical informatics, and has a sustained, outstanding record of leadership and service to the ACM and the computing community."

Duncan earned a Ph.D. in biostatistics from the University of Oklahoma. She has worked as an associate professor at the Medical University of South Carolina, as a member of the technical staff at the Mitre Corporation, and as an independent consultant..

Duncan is the author of the books Health Information and Health Reform: Understanding the Need for a National Health Information System (Jossey-Bass, 1994). and Community Health Information Systems: Lessons for the Future (Health Information Press, 1998).ACM Digital Library entry for Community Health Information Systems, retrieved 2015-06-30.

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