Euphorbia mercurialina, commonly called mercury spurge, is a species of plant in the spurge family.

It is native to the Southeastern United States, where it is primarily found in the vicinity of the Cumberland Plateau in east Tennessee and northern Alabama, and in the southern Appalachian Mountains. Disjunct populations are also found in the Piedmont of North Carolina.Flora of North America Euphorbia mercurialina Its natural habitat is in rich forests over calcareous rock.Flora of the Southern and Mid-Atlantic States

It flowers and fruits in the spring.

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