UIE may refer to:
United in Europe, political party in the UK (2014–2015) Union of Economic Interests, political party in Portugal (1925–1927) Unidentified infrared emission, in astronomy, also referred to as UIR UNESCO Institute for Education, one of six educational institutes of UNESCO User interface engineering, the design of user interfaces for machines and software Union Internationale des Étudiants, the International Union of Students (IUS), established in 1946 during the Cold War, with a pro-USSR stance