Esper is a surname, and may refer to:
Duke Esper (1868–1910), American professional baseball player Dwain Esper (1892–1982), American film director and producer Eugenius Johann Christoph Esper (1742–1810), German entomologist George Esper (1932–2012), American journalist Jan Esper (born 1968), German scientist Mark Esper (born 1964), American politician Michael Esper (born 1976), American actor