Gile is a surname. Notable people with the surname include:
Dennis Gile (born 1981), American football player Don Gile (born 1935), American baseball player Frank S. Gile (1847–1898), American sailor Jacob M. Gile (1849–1937), American architect and builder Kenneth L. Gile (born 1947), American businessman Krista Gile, American statistician Mary Stuart Gile (1936-2019), American politician Ransom Henry Gile (1836–1916), American settler Selden Connor Gile (1877–1947), American painter