Mixcoatlus is a small genus of pit vipers endemic to Mexico. The genus was described in 2011.

The name Mixcoatlus is derived from the Nahuatl word Mixcoatl or "cloud serpent", a deity of the Aztec and several other Mesoamerican civilizations. This name also refers to the geographic restriction of this clade to elevations above 2,000 meters.

Species There are three species: Mixcoatlus barbouri (Dunn, 1919) Mixcoatlus browni (Shreve, 1938) Mixcoatlus melanurus (Müller, 1923)

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