Huapaya is a surname, and may refer to:
Huapaya derives from wapa which means coffee colored alpaca in Quechua and ya from the Spanish expression ¡Ya està! (there it is).
Alfonso Huapaya Cabrera - Peruvian football player José Moisela Huapaya - Peruvian football player Marcial Francisco Buitrón Huapaya - Mayor of Punta Negra from 1990 to 2002