Wyke may refer to:
Places in England Wyke, North Dorset, an area of Gillingham Wyke Regis, Dorset Wyke, Shropshire Wyke Champflower, Somerset Wyke, Surrey Wyke, Bradford, an area of Bradford, West Yorkshire Wyke, an area of Kingston upon Hull, East Riding of Yorkshire Wyke College, a school Wike, West Yorkshire, a hamlet in Leeds district, West Yorkshire
People Charlie Wyke (born 1992), English footballer Charles Lennox Wyke (1815-1897), British diplomat John atte Wyke (fl.1373-1386), English MP Maria Wyke (born 1957), English professor of Latin Roger Wyke (died c.1467), English member of Parliament
Broadcast call signs WYKE-CD, a low-power television station (channel 24, virtual 47) licensed to serve Inglis/Yankeetown, Florida, United States WXZC, a radio station (104.3 FM) licensed to serve Inglis, Florida, which held the call sign WYKE from 2011 to 2018
See also Lower Wyke, Hampshire, England Middle Wyke, Hampshire, England North Wyke, Devon, England Wyke Farms Wyke House, Middlesex, England Wykes, a surname