Espina is a Spanish, Astur-Leonese and Catalan surname. Notable people with the surname include:
Concha Espina (1869–1955), Spanish writer Gerardo Espina, Jr (born 1970), Filipino politician Gretchen Espina (born 1988), Filipino singer and actress Marcelo Espina (born 1967), Argentine retired footballer Darío Espina Pérez (1920–1996), Cuban exile Gustavo Adolfo Espina Salguero (1946–2024), 30th President of Guatemala Carlos Eduardo Espina (born 1998), Uruguayan-American activist and social media personality
See also Lina Espina-Moore (1919–2000), Cebuano writer Fernando Martín Espina (1962–1989), Spanish basketball player, brother of Antonio Martín Espina Antonio Martín Espina (born 1966), Spanish basketball player, brother of Fernando Martín Espina La Espina, a parish in Salas, Asturias, Spain Espinas, a commune in southern France Espinas (surname) Espina (band) Mexican heavy metal / hard rock band