Acetylpyrazine is an organic compound with the chemical formula . It is a yellow-brown powder at room temperature. Chemically, acetylpyrazine is a pyrazine and a ketone. Natural occurrence Acetylpyrazine is found in foods such as seeds, nuts and meats. Uses It is used in frozen dairy products such as ice cream.

It is considered generally recognized as safe by the U.S. Food and Drug Administration.

"Essence formula for increasing cigarette fragrance and improving smoke quality".Mao Deshou, et al. CN115216363 (2022 to China Tobacco Yunnan Industrial Co Ltd).

It is also known to be part of the formulation of e-cigarettes (vapes):

Synthesis Note that modern synthesis is for 2-cyanopyrazine from 2-methylpyrazine [109-08-0].

Pyrazinamide [98-96-4] (1) 2-Cyanopyrazine [19847-12-2] (2)

More modern syntheses have also been reported in recent years:Wang et al.: Progress in the Synthesis and Application of Acetylpyrazine, 2011.任伟, et al. CN106588785 (2017 to Yoshida Spice Ltd By Share Ltd Shandong).

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