The International Society for Extracellular Vesicles (ISEV) is an international scientific organization that focuses on advancing global extracellular vesicle (EV) research. These membrane-bound particles are released from all known cells and include exosomes, ectosomes, exophers, oncosomes, and more. Established in 2011, the society is a nonprofit organization. It is governed by a Board of Directors and Executive Committee. The current president is Benedetta Bussolati. Previous presidents were Kenneth Witwer (2024-2026), Edit Buzás (2022-2024), Clotilde Théry (2018-2022), Andrew Hill (2016-2018) and founding president Jan Lötvall (2011-2016). The society's journals are the Journal of Extracellular Vesicles and the Journal of Extracellular Biology. ISEV also publishes the international consensus guidelines for EV studies, the "Minimal information for studies of EVs" (MISEV).
ISEV has several committees (Meetings and Programs, Science and Journals, Rigor and Standardization, Education, Translation, Regulation, and Advocacy Committee, and Communications and Membership) focused on advancing research and promoting awareness in the EVs. Each committee has specific roles and goals.
Meetings As part of its mission to promote scientific research and education, the society hosts annual meetings and educational event as well as numerous workshops on defined EV-related topics. The society also co-sponsors or endorses related events. Annual meetingLocationISEV2027Busan, South KoreaISEV2026San Juan, Puerto Rico ISEV2025Vienna, AustriaISEV2024Melbourne, AustraliaISEV2023Seattle, USAISEV2022Lyon, FranceISEV2021Virtual MeetingISEV2020Virtual MeetingISEV2019Kyoto, JapanISEV2018Barcelona, SpainISEV2017Toronto, CanadaISEV2016Rotterdam, NetherlandsISEV2015Washington DC, USAISEV2014Rotterdam, NetherlandsISEV2013Boston, USAISEV2012Gothenburg, Sweden
Workshops and scientific seminars ISEV workshops began with a meeting on extracellular RNA (New York City, 2012), and continue to include one to two meetings per year. During widespread restrictions on in-person meetings during the COVID-19 pandemic, ISEV introduced the "Extracellular Vesicle Club," a weekly virtual event featuring presentations and moderated discussion of scientific publications. TopicLocationYearISEV Cardiovascular Research (ISEV-CVR)United KingdomDecember 2026ISEVxTech 2026United StatesNovember 2026Bacterial and Viral Vesicles: Biogenesis, Communication, and Translational ApplicationChinaSeptember 2026EVs in ImmunityGreeceNovember 2025Second Symposium on EVs in Nervous SystemCanadaOctober 2025Education Day on Single EV Characterization of Genitourinary System EVs VirtualFebruary 2025Blood EVsSouth KoreaSeptember 2024Large Extracellular VesiclesUnited StatesMarch 2024EV-based BiomarkersDenmarkOctober 2023Workshop by EV-TRACK Task ForceVirtualMarch 2023The Second Urine EV Task Force Virtual Symposium on Urinary Extracellular VesiclesVirtualFebruary 2023QuantitatEVs: Multiscale analyses, from bulk to single vesicleRome and MilanJanuary-February 2023Blood EVs: an ISEV WorkshopFinlandSeptember 2022massivEVs WorkshopItaly/VirtuallyOctober 2021Infectious Diseases MeetingVirtualJanuary 2021EV Imaging in VivoFranceSeptember 2020EVs in ImmunologyBuenos AiresMarch 2020Open, Reproducible and Standardized EV ResearchBelgiumDecember 2019EV-based Clinical TheranosticsChinaNovember 2018Membranes and EVs WorkshopUnited StatesMarch 2018Extracellular Vesicles as Biomarkers of DiseaseUnited KingdomDecember 2017Diet, Environment and Extracellular VesiclesAustraliaJanuary 2017Cross-Organism Communication by Extracellular Vesicles: Hosts, Microbes, ParasitesBrazilNovember 2016Research Seminar: EV-associated RNA: Is there a purpose?NetherlandsSeptember 2015ISEV Workshop on Isolation and Characterization of Extracellular VesiclesHungaryOctober 2013ISEV RNA WorkshopUnited StatesOctober 2012
Endorsed or co-sponsored events The society has directly or indirectly supported EV-related events around the world. These include meetings of the UK, French, and Spanish and Portuguese EV Societies (GEIVEX), a course of the European Molecular Biology Laboratory, Keystone Symposia (2016 and 2018), Gordon Research Conferences (2016, 2018, and 2022), a Cold Spring Harbor Asia Meeting (2016), and others.
Journal of Extracellular Vesicles, Journal of Extracellular Biology, and standardization initiatives To disseminate research in the field, the society established the peer-reviewed open access Journal of Extracellular Vesicles in 2012. The journal was initially published by Co-Action Publishing, by Taylor & Francis from 2016 to 2020, and by Wiley since 2020. In addition to research and review articles, the journal periodically publishes position papers of the society that are meant to advance standardization efforts. In 2014, the Executive Board of Directors published a set of minimal information guidelines for publication of EV studies. These requirements, known as "MISEV" or "MISEV2014," mirrored similar initiatives in the fields of microarray (MIAME) and proteomics (MIAPE) analysis, among others. In 2017, the society's board announced its intent to update these requirements with community involvement. The "MISEV2018" requirements were published in 2018 by Clotilde Théry and Kenneth Witwer with input from 380 co-authors. The current consensus guidelines, known as "MISEV2023", were prepared with input from more than 1050 co-authors, using extensive crowdsourcing of expert opinion to build consensus. The corresponding authors are Joshua Welsh, Deborah Goberdhan, Lorraine O'Driscoll, Clotilde Théry and Kenneth Witwer.
In 2021, ISEV founded a second journal, the Journal of Extracellular Biology, focusing on EVs but also other extracellular particles (EPs) and phenomena. The editor-in-chief is Andrew Hill.
Education Among the educational initiatives of the society are massive open online courses (MOOCs), launched in 2016. MOOC 1&II are available through Coursera and co-sponsored by the University of Gothenburg, Pohang University of Science and Technology, and the University of California, Irvine. MOOC III is available on YouTube
Student Network on Extracellular Vesicles In 2020, the Student Network on Extracellular Vesicles (SNEV) was founded as a virtual network for early-career researchers in EV research. SNEV's activities include organizing online scientific talks, a monthly newsletter, industry talks and informal meet-and-greets (coffee catch ups). SNEV has organized two virtual conferences, one in 2021 and the second in 2023. Since 2024, SNEV has become the official early career entity within ISEV. [TD1]Link to Student Network on Extracellular Vesicles (wordpress.com)
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