Great River may refer to:

Rivers Great River (Grenada) Great River (Jamaica) Mississippi River, from the Ojibwe name Misi-ziibi, meaning "Great River" Nahr al-Kabir al-Janoubi, Arabic for "Great River" Connetquot River, New York, an Algonquian (Native American) word meaning "Great River" Bolshaya (river), in Russia

Places Great River, New York Great River station

Film and literature Great River: The Rio Grande in North American History, a non-fiction book by Paul Horgan Great River (film), a 2010 Canadian film Anduin, a river in J. R. R. Tolkien's fictional Middle-earth, is also known as the Great River of Wilderland Great River of Narnia, in C. S. Lewis's fictional world

Other Great River Regional Library, a multi-county public library system in the U.S. State of Minnesota

See also Grand River (disambiguation) Big River (disambiguation)