William Wise or Bill Wise may refer to:
William Furlong Wise (1784–1844), British naval officer Bill Wise (baseball) (1861–1940), American baseball player William Wise (author) (born 1923), American author of children's literature Willie Wise (born 1947), American basketball player Willy Wise (born 1967), American boxer William Wise III (born 1992), American basketball player Bill Wise, American actor
See also William Wiseman (disambiguation)