Catharine is a feminine given name, a variation of Katherine or Catherine. Notable people with the name include:
In education: Catharine Beecher, noted educator Catharine Paine Blaine, American teacher and suffragist Catharine MacKinnon, American feminist, scholar, lawyer, teacher, and activist Catharine Merrill, one of the first female university professors in the United States
In literature: Catharine Webb Barber (1823-?), American newspaper editor, author Catharine Carver (1921–1997), American-British publisher's editor Catharine H. Esling (1812–1897), American writer Catharine Hitchcock Tilden Avery, 1844–1911), American author, editor, educator Catharine Trotter Cockburn, 1679–1749), English novelist, dramatist, philosopher Catharine Sedgwick, American novelist
In science: Catharine Cox, American psychologist known for her work on intelligence and genius Catharine Garmany, astronomer
In rulers: Catherine the Great, Empress of Russia from 1762 till 1796 known as the country's longest-ruling female.
Other: Catharine (Tennessee), an enslaved American mother born about 1835