DeCicco is a surname. Notable people with the surname include:
Dom DeCicco (born 1988), American football player Frank DeCicco (1935–1986), American mobster George DeCicco (1929–2014), American mobster Mike DeCicco (1927–2013), American fencing coach
See also Anne Marie DeCicco-Best (born 1964), Canadian mayor De Cicco v. Schweizer, a United States contract law case DeCicco's, a family-owned chain of supermarkets in the northern suburbs of New York City