E4, E.IV or E-4 may refer to:

Entertainment E4 (TV channel), a television channel in the United Kingdom and Ireland Every Extend Extra Extreme, a video game from Q Entertainment Entertainment for All, a video game expo

Transportation Aero Asia International, an airline, by IATA code

Roads Central Expressway (Sri Lanka), numbered E04 European route E4, a road through Finland and Sweden E4 European long distance path, a European long-distance trail Tōhoku Expressway, route E4 in Japan E4 expressway (Pakistan) South Kedah Expressway in Malaysia Subic Freeport Expressway in the Philippines

Trains E4 Series Shinkansen, a Japanese high-speed train CNW Class E-4, a 4-6-4 steam locomotive of the Chicago & Northwestern Railway EMC E4, a diesel locomotive LB&SCR E4 class, a steam locomotive of the London, Brighton & South Coast Railway LNER E4 Class, a 2-4-0 steam locomotive built by the Great Eastern Railway and operated by the LNER

Military Boeing E-4, a U.S. military flying command post Fokker E.IV, a 1915 German fighter aircraft E4, the fourth enlisted rank in the Military of the United States, including: Petty officer third class in the United States Navy and United States Coast Guard Senior airman in the United States Air Force (Sergeant until 1976) Specialist (rank) in the United States Army (if the soldier is not a non-commissioned officer) Corporal in the United States Army and United States Marine Corps (if the soldier is a non-commissioned officer)

Science and technology E4-isoprostane, a type of isoprostane Leukotriene E4, a naturally produced eicosanoid lipid mediator E-4 process, an obsolete development process associated with photographic transparency film Honda E4, a predecessor of Honda's ASIMO robot RCS-4, a synthetic cannabinoid sold as "E-4" E4 or E4, an old name for the exceptional group F4 Estetrol, an estrogen

Other uses Big Four (Western Europe), sometimes called 'E4', a group of powerful countries in Europe E4, a postcode district in the E postcode area King's Pawn Game, or 1. e4, a chess opening move E4 grade, a grade of difficulty in rock climbing E4 or E4, musical notation indicating the E above Middle C

See also 4E (disambiguation) EIV (disambiguation)