Southworth may refer to:
People Southworth (surname)
Places Southworth, Ohio, an unincorporated community Southworth, Washington – unincorporated community on Puget Sound in Kitsap County, Washington Point Southworth – on Kitsap Peninsula on the western side of the northern entrance to Colvos Passage in Puget Sound Southworth Creek, a stream in Oregon
Others uses Southworth & Hawes – an early photographic firm in Boston.