S25 can refer to:

Aircraft Blériot-SPAD S.25, a French biplane Letov Š-25, a Czechoslovak biplane trainer Short S.25 Sandringham, a British flying boat airliner Short S.25 Sunderland, a British flying boat bomber Sikorsky S-25, a Russian biplane bomber Spalinger S.25, a Swiss training glider

Roads County Route S25 (California) County Route S25 (Bergen County, New Jersey) New Jersey Route 413, numbered S25 until 1953

Rail and transit S25 (Berlin), a line on the Berlin S-Bahn, Germany S25 (Long Island bus), United States S25 (St. Gallen S-Bahn), an S-Bahn service operating over the Rorschach–Heiden railway line, Switzerland S25 (ZVV), a line of the Zurich S-Bahn, Switzerland S25, an Aargau S-Bahn line, Switzerland Niseko Station, in Hokkaido, Japan

Other uses S-25 (rocket), a Soviet air-to-ground rocket 40S ribosomal protein S25, a eukaryote-specific protein British NVC community S25, a swamps and tall-herb fens community in the British National Vegetation Classification system , a submarine of the Indian Navy S25: Avoid contact with eyes, a safety phrase S-25 Berkut, a Soviet surface-to-air missile system Siemens S25, a Siemens Mobile phone , a submarine of the United States Navy S25, a postcode district in Sheffield, England Samsung Galaxy S25, a series of high-end Android smartphones developed by Samsung Electronics