Tremezzina (Comasco: ) is a comune in the province of Como, in Lombardy, that formed on 25 May 2014Fusione Comuni, 9 nuove amministrazioni al voto il 25 maggio from a merger of the comunes of Lenno, Mezzegra, Ossuccio and Tremezzo.

A referendum to create this comune was held on 1 December 2013. The referendum was passed with 63% yes and 37% no votes.

The comune of Tremezzina was previously created in 1928R.D. 6 dicembre 1928, n. 3172 over Lenno, Mezzegra and Tremezzo, and divided into the separate comunes in 1947.D.L.C.p.S. 20 agosto 1947, n. 977

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