Bluffton may refer to:
Places in Canada Bluffton, Alberta
Places in the United States Bluffton, Alabama Bluffton, Arkansas Bluffton Colony, a part of Muskegon, Michigan, which included a colony of vaudeville actors, including Buster Keaton. Bluffton, Georgia Bluffton, Indiana Bluffton, Minnesota Bluffton, Ohio Bluffton University Bluffton, Texas Bluffton, South Carolina Bluffton Township, Minnesota
Other Bluffton Movement, 1844, South Carolina political group